The Mediterranean is one of the “laboratories” of the global warming impacts. In the Mediterranean area, climate change is running at a rate 20% higher than the global average, and the pre-industrial temperature has already been exceeded by a range from 1.2 to 3°, with climate variables compromised. This makes the Mediterranean region a hotspot of climate change impacts with prolonged rainfall deficits and weather events with high magnitude and real tropical hurricanes known as Medicane, which have effects on water and natural environment, agriculture, urban areas, health and migration.